Skip to main content
Poultria Poultria

Poultria Home

Veterinary Reviewed

Ulcerative Enteritis / Quail Disease (Clostridium colinum) Guide

Veterinary reference covering Clostridium colinum endospores, button ulcers in ceca, hepatic yellow necrosis, and Bacitracin therapy.

Scientific Overview

Ulcerative Enteritis (Quail Disease) is an acute, infectious bacterial enteritis caused by Clostridium colinum. Affecting quail, young broilers, and poults, it causes severe hemorrhagic-to-ulcerative enteritis, deep circular button ulcers in the intestine and ceca, and liver necrosis with high mortality (up to 100% in quail).

Etiology & Endospore Persistence

Spores are shed in droppings and persist indefinitely in soil and litter. Flies act as mechanical vectors transferring spores between pens.

Necropsy Pathology: Button Ulcers & Liver Necrosis

Pathognomonic post-mortem lesions:

  • Intestinal & Cecal Ulcers: Deep, rounded, raised 'button-like' necrotic ulcers throughout the ileum and ceca, often perforating the gut wall to cause fatal peritonitis.
  • Hepatic Yellow Necrosis: Liver is enlarged with yellow-white necrotizing lesions or large pale yellow areas along organ borders.
  • Splenomegaly: Spleen is dark red, congested, and enlarged.

Treatment & Prophylaxis

Treatment requires water-soluble Bacitracin, Tetracyclines, or Erythromycin. Prevention relies on maintaining dry litter, wire floor housing for game birds, and fly control.